Every now and then measurements or chemical analyses show up in the awarded Nobel prize descriptions.

I recently came across the Nobel lecture of John B. Fenn, the inventor (together with Koichi Tanaka) of the ESI ionization method for mass spectrometry. ESI ionization allows obtaining mass spectra of very large and delicate molecules without breaking them. This ionization method is used in more than three fourths of all mass-spectrometric measurements made today. For this invention Fenn and Tanaka were awarded the 2002 Nobel prize in chemistry.

The Nobel lecture of John B. Fenn is a very good overview of the topic from history perspective. Can be recommended to everyone involved in ESI-MS.

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